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Eur J Neurol. 2014;21(1):167-70. doi: 10.1111/ene.12081. Epub 2013 Jan 11.

Cannabis and other illicit drug use in epilepsy patients.

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  • 1Department of Neurology, Charité-University Hospital Berlin, Berlin, Germany.

Abstract

BACKGROUND AND PURPOSE:

This study aimed to assess the prevalence of illicit drug use among epilepsy patients and its effects on the disease.

METHODS:

We systematically interviewed epilepsy outpatients at a tertiary epilepsy clinic. Predictors for active cannabis use were analysed with a logistic regression model.

RESULTS:

Overall, 310 subjects were enrolled; 63 (20.3%) reported consuming cannabis after epilepsy was diagnosed, and 16 (5.2%) used other illicit drugs. Active cannabis use was predicted by sex (male) [odds ratio (OR) 5.342, 95% confidence interval (95% CI) 1.416-20.153] and age (OR 0.956, 95% CI 0.919-0.994). Cannabis consumption mostly did not affect epilepsy (84.1%). Seizure worsening was observed with frequent illicit (non-cannabis) drug use in 80% of cases.

CONCLUSIONS:

Cannabis use does not seem to affect epilepsy; however, frequent use of other drugs increases seizure risk.

© 2013 The Author(s) European Journal of Neurology © 2013 EFNS.

KEYWORDS:

amphetamines; cocaine; epidemiology; epilepsy; epileptic seizures; illicit drugs; marijuana

PMID:
23311572
[PubMed - indexed for MEDLINE]
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