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Tohoku J Exp Med. 1990 Jan;160(1):93-4.

Probable assignment of the dihydropteridine reductase gene to 4p15.31.

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  • 1Department of Pediatrics, Nagoya City University Medical School.


We report the dihydropteridine reductase (DHPR) activity in cases with interstitial deletion of the short arm of chromosome 4. Case 1 with the segment 4p15.32-4p16 deleted has normal DHPR activity. Case 2 with 4p15.2-4p15.32 deleted has reduced DHPR activity, less than 50% of normal.

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