The study developed and tested collaboration models for home medication reviews (HMR) between community pharmacies and general practitioner (GP)s. Three pairs (each comprising one pharmacist and one GP) developed a collaboration agreement on the patient group, content and place for HMR, responsibilities, continuation etc. The collaboration models were evaluated by the pairs and by a project group. The models were very different - adjusted to the GP's and the pharmacist's individual wishes. The entering of collaboration agreements is a good platform for effective cooperation between the pharmacist and the GP and leads to successful HMRs. We recommend that others develop collaboration models too.