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Chem Pharm Bull (Tokyo). 2013;61(1):105-7.

Himeic acids E-G, new 4-pyridone derivatives from a culture of Aspergillus sp.

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  • 1Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 862-0973, Japan.

Abstract

Three new himeic acids E-G were isolated from a marine-derived fungus, Aspergillus sp., and their structures were determined by spectroscopic analysis. Although himeic acid A inhibited the activity of ubiquitin-activating enzyme (E1), the three new derivatives did not.

PMID:
23302594
[PubMed - indexed for MEDLINE]
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