Format

Send to:

Choose Destination
See comment in PubMed Commons below
J Colloid Interface Sci. 2013 Mar 15;394:590-7. doi: 10.1016/j.jcis.2012.11.041. Epub 2012 Dec 5.

Amino and carboxyl plasma functionalization of collagen films for tissue engineering applications.

Author information

  • 1Dept. of Biotechnology and Biosciences, University of Milano-Bicocca, P.zza della Scienza 2, 20126 Milano, Italy.

Abstract

Type I collagen films have been functionalized on their surfaces by plasma treatment with carboxyl and amino groups to improve their potential for grafting bioactive molecules. The physico-chemical properties of the plasma-treated films were evaluated and compared to the untreated materials by water contact angle, SEM and AFM. The presence of new functional groups on the film surfaces has been assessed by ATR-FTIR spectra after chemical derivatization. Moreover, the biocompatibility of the plasma-treated films was studied with MG-63 human osteoblast-like cells, evaluating cell proliferation, viability and morphology at 1, 3 and 7 days.

Copyright © 2012 Elsevier Inc. All rights reserved.

PMID:
23266023
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk