Send to:

Choose Destination
See comment in PubMed Commons below
Chem Soc Rev. 2013 May 21;42(10):4284-96. doi: 10.1039/c2cs35416k. Epub 2012 Dec 21.

Chemical probing of glycans in cells and organisms.

Author information

  • 1Department of Biochemistry, Yeshiva University, 1300 Morris Park Ave, Bronx, NY 10461, USA.


Among the four major building blocks of life, glycans play essential roles in numerous physiological and pathological processes. Due to their non-templated biosynthesis, advances towards elucidating the molecular details of glycan functions are relatively slow compared with the pace of protein and nucleic acid research. Over the past 30 years, chemical tools have emerged as powerful allies to genetics and molecular biology in the study of glycans in their native environment. This tutorial review will provide an overview of the recent technological developments in the field, as well as the progress in the application of these techniques to probe glycans in cells and organisms.

[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Royal Society of Chemistry Icon for PubMed Central
    Loading ...
    Write to the Help Desk