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AJR Am J Roentgenol. 2013 Jan;200(1):50-6. doi: 10.2214/AJR.12.8500.

Tumefactive cerebral amyloid angiopathy mimicking CNS neoplasm.

Author information

  • 1Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA. kotsenas.amy@mayo.edu

Abstract

OBJECTIVE:

The tumefactive variant of cerebral amyloid angiopathy (CAA) is rare. In this article we describe imaging findings associated with this entity and evaluate the role of susceptibility MRI sequences in its diagnosis.

CONCLUSION:

Our findings suggest that in elderly patients, susceptibility sequences should be part of prebiopsy MRI for tumefactive lesions. Identification of characteristic diffuse microhemorrhages should prompt inclusion of CAA in the differential diagnosis, targeted biopsy of the cortex and leptomeninges, and pathologic staining for CAA.

PMID:
23255741
[PubMed - indexed for MEDLINE]
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