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J Pharm Bioallied Sci. 2012 Oct;4(4):282-5. doi: 10.4103/0975-7406.103238.

Evaluating the anti-plaque efficacy of meswak (Salvadora persica) containing dentifrice: A triple blind controlled trial.

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  • 1Department of Public Health Dentistry, Teerthankar Mahaveer Dental College and Research Centre, Moradabad, Uttar Pradesh, India.

Abstract

INTRODUCTION:

The growing field of alternative medicine has shown that dentifrices based on plant extracts are available in the market but there is little or no research to prove or refute the efficacy of dentifrices containing combination of herbal components.

AIM:

The study was conducted to evaluate the anti-plaque efficacy of a commercially available Meswak containing dentifrice compared to the conventional dentifrice using a randomized, triple blind, parallel design method.

MATERIALS AND METHODS:

A total of 350 subjects were selected. All the subjects (aged 13-54 years) were given the test dentifrices, packed in plain white color-coded tubes. The subjects were instructed to brush their teeth twice daily for 2 min with the allocated dentifrice. The total study duration was 4 weeks. Plaque scores were recorded at the baseline, 2 weeks and 4 weeks respectively, using the Turesky modification of the Quigley Hein Plaque Index.

RESULTS:

The results showed that there were significant differences in the reduction of plaque by the herbal dentifrice, Meswak (Salvadora persica) on intra-group and inter-group comparison.

CONCLUSION:

It was concluded that further research is required to know the dental benefits of herbal products being incorporated into the commercially available dentifrices.

KEYWORDS:

Clinical trial; Meswak; herbal dentifrices; plaque index; randomized parallel design; triple blind study

PMID:
23248560
[PubMed]
PMCID:
PMC3523522
Free PMC Article
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