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Toxins (Basel). 2012 Oct 25;4(11):1024-57. doi: 10.3390/toxins4111024.

Current understanding on aflatoxin biosynthesis and future perspective in reducing aflatoxin contamination.

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  • 1Southern Regional Research Center, Agricultural Research Service, United States Department of Agriculture (USDA/ARS), New Orleans, LA 70112, USA.


Traditional molecular techniques have been used in research in discovering the genes and enzymes that are involved in aflatoxin formation and genetic regulation. We cloned most, if not all, of the aflatoxin pathway genes. A consensus gene cluster for aflatoxin biosynthesis was discovered in 2005. The factors that affect aflatoxin formation have been studied. In this report, the author summarized the current status of research progress and future possibilities that may be used for solving aflatoxin contamination.

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