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Sensors (Basel). 2012 Oct 30;12(11):14604-11. doi: 10.3390/s121114604.

Performance of Eudragit coated whispering gallery mode resonator-based immunosensors.

Author information

  • 1Istituto di Fisica Applicata Nello Carrara (IFAC CNR), 50019 Sesto Fiorentino, Firenze, Italy. a.giannetti@ifac.cnr.it

Abstract

Whispering gallery mode resonators (WGMR) are an efficient tool for the realization of optical biosensors. A high Q factor preservation is a crucial requirement for good biosensor performances. In this work we present an Eudragit®L100 coated microspherical WGMR as an efficient immunosensor. The developed resonator was morphologically characterized using fluorescence microscopy. The functionalization process was tuned to preserve the high Q factor of the resonator. The protein binding assay was optically characterized in terms of specificity in buffer solution.

PMID:
23202178
[PubMed - indexed for MEDLINE]
PMCID:
PMC3522931
Free PMC Article

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