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Stem Cells Transl Med. 2012 Feb;1(2):136-41. doi: 10.5966/sctm.2012-0030. Epub 2012 Jan 26.

Concise review: cell therapy and tissue engineering for cardiovascular disease.

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  • 1Institute of Advanced Biomedical Engineering and Science, TWIns, Tokyo Women's Medical University, Tokyo, Japan.

Abstract

Cardiovascular disease is a major cause of morbidity and mortality, especially in developed countries. Various therapies for cardiovascular disease are investigated actively and are performed clinically. Recently, cell-based regenerative medicine using several cell sources has appeared as an alternative therapy for curing cardiovascular diseases. Scaffold-based or cell sheet-based tissue engineering is focused as a new generational cell-based regenerative therapy, and the clinical trials have also been started. Cell-based regenerative therapies have an enormous potential for treating cardiovascular disease. This review summarizes the recent research of cell sources and cell-based-regenerative therapies for cardiovascular diseases.

PMID:
23197760
[PubMed - indexed for MEDLINE]
PMCID:
PMC3659688
Free PMC Article
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