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Adv Healthc Mater. 2012 Nov;1(6):762-7. doi: 10.1002/adhm.201200182. Epub 2012 Aug 27.

Hybrid conducting polymer-hydrogel conduits for axonal growth and neural tissue engineering.

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  • 1Department of Bioengineering, Pennsylvania State University, University Park, PA 16802, USA.


Successfully and efficiently bridging peripheral nerve gaps without the use of autografts is a substantial clinical advance for peripheral nerve reconstructions. Novel templating methods for the fabrication of conductive hydrogel guidance channels for axonal regeneration are designed and developed. PEDOT is electrodeposited inside the lumen to create fully coated-PEDOT agarose conduits and partially coated-PEDOT agarose conduits.

Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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