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Adv Healthc Mater. 2012 Sep;1(5):635-9. doi: 10.1002/adhm.201200158. Epub 2012 Jul 25.

Cellular hydrogel biopaper for patterned 3D cell culture and modular tissue reconstruction.

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  • 1Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 305-701, Republic of Korea.

Abstract

Microarchitectured freestanding cellular hydrogel biopaper as a novel 3D cell culture or tissue reconstruction module is reported. New harvesting, transfer, and assembly techniques are used to construct laminated tissue composites of the biopaper, such as hepatic hydrogel sheet modules with augmented liver function for stratified 3D hepatic tissue reconstruction.

Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

PMID:
23184799
[PubMed - indexed for MEDLINE]
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