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J Cancer Res Ther. 2012 Jul-Sep;8(3):427-9. doi: 10.4103/0973-1482.103525.

Adjuvant pelvic irradiation for cervical cancer in the setting of a transplanted pelvic kidney.

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  • 1Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA. majid.mohiuddin.md@gmail.com

Abstract

Postoperative radiation therapy is often needed following resection for gynecological cancers. A pelvic kidney, whether ectopic or transplanted, is considered an absolute contraindication for radiation if the organ is left in place. A 45-year-old, immunosuppressed patient with FIGO IB1 cervical adenocarcinoma was treated with intensity-modulated radiation therapy (IMRT) to 45 Gy to the modified whole pelvis with a boost to 59.4 Gy to high-risk areas despite having a transplanted kidney in the right iliac fossa. The irradiation prevented further local failure in the pelvis at 36-month follow-up with no decrement in renal function. Radiation to the modified pelvis using IMRT while avoiding the renal allograft is technically feasible and should be offered to more high-risk patients.

PMID:
23174727
[PubMed - indexed for MEDLINE]
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