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Hua Xi Kou Qiang Yi Xue Za Zhi. 2012 Oct;30(5):501-4.

[Study of the pragmatic of saliva test cassette to detect the Helicobacter pylori in oral cavity].

[Article in Chinese]

Author information

  • 1Dept. of Stomatology, Peking University First Hospital, Beijing 100034, China.

Abstract

OBJECTIVE:

To study the link of Helicobacter pylori salive test cassette (HPS) and 13C-urea breath test (13C-UBT) on detecting Helicobacter pylori infection of stomach, and the sensitivity as well as specificity should be determined.

METHODS:

A screening trial of 13C-UBT and HPS tests was carried out 130 patients included 106 positive and 24 negative results of 13C-UBT. As gold standards of 13C-UBT, a comparison study with HPS was evaluated using Bayes formula.

RESULTS:

The sensitivity, specificity, accuracy, positive and negative predictive value of HPS was 68.87%, 58.33%, 66.92%, 87.95%, 29.79% respectively. The coincidence was 66.92%.

CONCLUSION:

There is a correlation between results of 13C-UBT and HPS. Combination of 13C-UBT and HPS may compensate the blind zone of 13C-UBT in detecting oral Helicobacter pylori infection. 13C-UBT could not be used as a gold standard to judge the validation of HPS in detecting Helicobacter pylori oral infection. The methods can be used at the same time in clinic.

PMID:
23173315
[PubMed - in process]
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