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Vasc Health Risk Manag. 2012;8:613-9. doi: 10.2147/VHRM.S29138. Epub 2012 Nov 15.

Treatment of prehypertension: lifestyle and/or medication.

Author information

  • 1Vascular Biology and Autonomic Studies Laboratory, Appalachian State University, Boone, NC, USA. colliersr@appstate.edu


Prehypertension is a warning to individuals with resting blood pressures between 120/80 mmHg and 139/89 mmHg of an insidious progression of blood pressure towards hypertensive levels (≥ 140/90 mmHg). Prehypertension is associated with increased cardiovascular risk and end organ damage compared with individuals who are normotensive. This review primarily focuses on internal and external factors associated with the prevalence of prehypertension. Elucidating all of the factors associated with a rise in resting blood pressure and comparing the effects of medication versus lifestyle changes may aid the clinician in developing a preventive and/or treatment strategy for each individual.


blood pressure; lifestyle changes; sex differences

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