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J Infect Dis. 2012 Dec 15;206 Suppl 1:S29-35. doi: 10.1093/infdis/jis573.

Viral etiology of influenza-like illnesses in Cameroon, January-December 2009.

Author information

  • 1Service de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroon. njouom@pasteur-yaounde.org

Abstract

BACKGROUND:

No information is available on the viral etiology of upper respiratory tract infections in Cameroon.

METHODS:

We prospectively enrolled outpatients with influenza-like illness (ILI) presenting at 14 sentinel clinics located across the country from January through December 2009. The specimens were tested using real-time and multiplex reverse-transcription polymerase chain reaction methods for the detection of 15 RNA respiratory viruses.

RESULTS:

We detected at least 1 respiratory virus in 365 of 561 specimens (65.1%). Overall, influenza virus was the most commonly detected virus (28.2% of specimens), followed by human rhinovirus (17.8%); parainfluenza virus (PIV) types 1-4 (7.5%); enterovirus (5.9%); respiratory syncytial virus (RSV; 5.7%); human coronavirus (HCoV) OC43, 229E, NL63, and HKU1 (5.3%); and human metapneumovirus (HMPV; 5.0%). RSV (26 of 31 specimens [83.9%]), PIV (30 of 39 [76.9%]), and HRV (64 of 99 [64.6%]) were most common among children <5 years of age. Coinfections were found in 53 of 365 positive specimens (14.5%), and most (71.7%) were in children <5 years of age. While influenza virus, enterovirus, RSV, and HMPV had a defined period of circulation, the other viruses were detected throughout the year.

CONCLUSIONS:

We found that respiratory viruses play an important role in the etiology of ILI in Cameroon, particularly in children <5 years of age.

PMID:
23169968
[PubMed - indexed for MEDLINE]
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