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Ocul Immunol Inflamm. 2012 Dec;20(6):460-3. doi: 10.3109/09273948.2012.723108. Epub 2012 Nov 19.

Fundus autofluorescence imaging in punctate inner choroidopathy with blind spot enlargement.

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  • 1Department of Ophthalmology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.



To present a case report in which fundus autofluorescence (FAF) helped to diagnose and monitor the clinical course of a patient diagnosed with punctate inner choroidopathy (PIC).


Retrospective chart review of patient data.


FAF showed multiple hypoautofluorescent spots in the posterior pole.It also showed an area of hypoautofluorescence surrounded by a ring of hyperautofluorescence, which corresponded to a larger lesion seen clinically. As the disease became inactive, the number of hypoautofluorescent spots decreased. The rim of hyperautofluorescence surrounding the macular lesion became attenuated.Persistent hypofluorescent areas grew in size.


FAF is a useful imaging modality to better visualize and delineate the extent of damaged retinal pigment epithelium (RPE) in PIC. FAF also helps the clinician to assess the resolution of the disease by the appearance of the RPE.

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