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Cardiovasc Interv Ther. 2013 Apr;28(2):170-7. doi: 10.1007/s12928-012-0147-7. Epub 2012 Nov 18.

Clinical implications of coronary pressure measurement after stent implantation.

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  • 1Department of Cardiology, Kyoto Second Red Cross Hospital, 355-5 Haruobi-cho, Kamanzadorimarutamachi, Kamigyo-ku, Kyoto 602-8026, Japan. kiakiko@mx4.canvas.ne.jp

Abstract

This study investigated the effect of fractional flow reserve (FFR) after stent implantation on clinical outcomes. Pressurewire measurements and follow-up data were obtained after stent implantation. Regarding the end point, target lesion revascularization (TLR) occurred in 11 patients (15.9%). Patients with TLR had higher frequencies of multiple stenting (54.5 vs. 19.0%, p = 0.01), lower post-interventional FFRs (0.84 vs. 0.88, p = 0.01), and longer stent lengths (42.20 vs. 27.69 mm, p = 0.01) than patients without TLR. The post-interventional FFR cutoff for TLR was 0.79, although this value had a weak discriminatory ability. However, multivariate analysis did not show any significant independent predictors of TLR (odds ratio 6.33; confidence interval 0.75-53.4, p = 0.09). Post-interventional FFR values were not significantly associated with TLR when a sub-analysis was performed in patients who underwent only drug-eluting stent (DES) implantation. It was difficult to achieve post-interventional FFRs of 0.9 or greater. DES implantation eliminated the effect of post-interventional FFR on TLR. Post-interventional FFR was not able to predict TLR in the present study.

PMID:
23161151
[PubMed - indexed for MEDLINE]
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