Format

Send to:

Choose Destination
See comment in PubMed Commons below
Surg Clin North Am. 2012 Dec;92(6):1463-74. doi: 10.1016/j.suc.2012.08.003. Epub 2012 Oct 13.

Mechanical ventilation.

Author information

  • 1Division of Critical Care and Acute Care Surgery, Department of Surgery, University of Minnesota, Minneapolis, MN 55455, USA. mmjames@umn.edu

Abstract

The treatment of respiratory failure requiring mechanical ventilation has advanced significantly over the last 20 years. The goal of therapy in patients with acute respiratory distress syndrome should be to optimize oxygenation while minimizing the risk of ventilator-induced lung injury and providing adequate ventilation. Appropriate use of ventilation modes and strategies, positive-end expiratory pressure levels, and recruitment maneuvers can improve oxygen delivery. Salvage therapies, such as prone positioning, inhaled epoprostenol and nitric oxide, and high-frequency oscillatory ventilation, have a well-established role in supportive management and are associated with improved oxygenation but not survival.

Copyright © 2012 Elsevier Inc. All rights reserved.

PMID:
23153879
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk