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Ticks Tick Borne Dis. 2012 Dec;3(5-6):361-3. doi: 10.1016/j.ttbdis.2012.10.018. Epub 2012 Nov 7.

The use of eschar swabs for the diagnosis of African tick-bite fever.

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  • 1Aix Marseille Université, Unité de Recherche en Maladies Infectieuses et Tropicales Emergentes (URMITE), UM63, CNRS 7278, IRD 198, Inserm 1095, WHO Collaborative Center for Rickettsioses and Other Arthropod Borne Bacterial Diseases, 27 bd Jean Moulin, 13385 Marseille Cedex 5, France.


African tick-bite fever (ATBF) caused by Rickettsia africae is a frequent cause of fever in returned travelers. Here, we used eschar swabs and/or eschar crust samples for the molecular diagnosis of ATBF in returned travelers. In 4 of 5 patients returning from South Africa, including 3 with negative serology, R. africae was identified by molecular tools targeting 2 different genes. The findings of this study highlight the usefulness of eschar swabs and/or eschar crust samples for the diagnosis of R. africae infection.

Copyright © 2012 Elsevier GmbH. All rights reserved.

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