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Anim Biotechnol. 2012;23(4):225-32. doi: 10.1080/10495398.2012.700290.

Single nucleotide polymorphisms of the bovine VEGF-B gene and their associations with growth traits in the Nanyang cattle breed.

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  • 1College of Animal Science and Technology, Northwest A&F University, ShaanxiKey Laboratory of Molecular Biology for Agriculture, Yangling, Shaanxi, China.

Erratum in

  • Anim Biotechnol. 2013 Jan;24(1):79.


PCR-SSCP and DNA sequencing methods were applied to reveal single nucleotide polymorphisms (SNPs) in the bovine VEGF-B gene in 675 samples belonging to three native Chinese cattle breeds. We found 3 SNPs and a duplication NC_007330.5: g. [782 A>G p. (Gly112 =) (;) 1000-1001dup CT (;) 1079 C>T (;) 2129 G>A p. (Arg184Gln)]. We also observed a statistically significant association of the polymorphism (1000-1001dup CT) in intron 3 of the VEGF-B gene with the body weight of the Nanyang cattle (p < 0.05). This polymorphisms of VEGF-B gene need to be verified among a larger cattle population before it can be identified as a marker for bovine body weight.

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