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Case Rep Radiol. 2012;2012:310359. doi: 10.1155/2012/310359. Epub 2012 Oct 22.

Medulloblastoma with excessive nodularity: radiographic features and pathologic correlate.

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  • 1The Department of Pediatrics, University of California San Diego and Rady Children's Hospital, 3020 Children's Way, San Diego, CA 92123, USA.

Abstract

Medulloblastoma with extensive nodularity is a rare subtype of the most common malignant childhood brain tumor and has been associated with more favorable prognosis. The authors report the case of a 10-month-old girl with a posterior fossa tumor of excessive nodularity with decreased diffusivity on diffusion-weighted magnetic resonance imaging sequences and robust grape-like postgadolinium contrast enhancing features. The unique neuroradiographic features were confirmed by histopathology and a diagnosis of medulloblastoma with extensive nodularity was made. This case highlights the importance of recognizing this unique medulloblastoma subtype preoperatively, as the more favorable outcome may preclude less aggressive medical management.

PMID:
23133782
[PubMed]
PMCID:
PMC3485496
Free PMC Article
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