Silicon nanowires as a rechargeable template for hydride transfer in redox biocatalysis

Nanoscale. 2012 Dec 21;4(24):7636-40. doi: 10.1039/c2nr32963h. Epub 2012 Nov 6.

Abstract

We report a new possible application of hydrogen-terminated silicon nanowires (H-SiNWs) as a rechargeable template for hydride transfer in redox biocatalysis. H-SiNWs transfer hydride efficiently to regenerate NADH by oxidizing Si-H(x) bonds. The oxidized H-SiNWs were readily recharged for the continuous regeneration of NADH and enzymatic reactions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biocatalysis
  • Hydrogen / chemistry
  • Hydrogen / metabolism
  • L-Lactate Dehydrogenase / metabolism
  • NAD / chemistry
  • NAD / metabolism
  • Nanowires / chemistry*
  • Oxidation-Reduction
  • Silicon / chemistry*

Substances

  • NAD
  • Hydrogen
  • L-Lactate Dehydrogenase
  • Silicon