Format

Send to:

Choose Destination
See comment in PubMed Commons below
Org Lett. 2012 Nov 16;14(22):5736-9. doi: 10.1021/ol302743k. Epub 2012 Nov 2.

α-Aryl-substituted allenamides in an imino-Nazarov cyclization cascade catalyzed by Au(I).

Author information

  • 1Division of Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin, Madison, Wisconsin 53705, USA.

Abstract

An imino-Nazarov cyclization using α-aryl-substituted allenamides is described. This gold(I)-catalyzed cascade is efficient and regioselective in constructing a diverse array of synthetically useful aromatic-ring fused cyclopentenamides. The success in this transformation represents a solution to the challenge in establishing an imino-Nazarov cyclization process.

PMID:
23121692
[PubMed - indexed for MEDLINE]
PMCID:
PMC3500446
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Chemical Society Icon for PubMed Central
    Loading ...
    Write to the Help Desk