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Genome Biol. 2012 Oct 31;13(10):175. doi: 10.1186/gb-2012-13-10-175.

The birth of the Epitranscriptome: deciphering the function of RNA modifications.

Abstract

Recent studies have found methyl-6-adenosine in thousands of mammalian genes, and this modification is most pronounced near the beginning of the 3' UTR. We present a perspective on current work and new single-molecule sequencing methods for detecting RNA base modifications.

PMID:
23113984
[PubMed - in process]
PMCID:
PMC3491402
Free PMC Article

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