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Contrast Media Mol Imaging. 2013 Jan-Feb;8(1):92-5. doi: 10.1002/cmmi.1481.

Gd2O3 nanoparticles: size-dependent nuclear magnetic resonance.

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  • 1School AME, University of South Australia, Mawson Lakes, Australia.


In this communication, we demonstrate that there is an optimum gadolinium oxide (Gd(2)O(3)) nanoparticle size of 2.3 nm; in the presence of Gd(2)O(3) particles smaller and larger than this critical size, the spin-lattice relaxation rate (T(1) = 1/r(1)) of water protons at 7.0 T drastically decreases. Since r(1) is directly related to the quality of magnetic resonance imaging, the results presented here have significant implications for clinical diagnostics.

Copyright © 2012 John Wiley & Sons, Ltd.

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