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Indian J Clin Biochem. 2005 Jul;20(2):195-7. doi: 10.1007/BF02867428.

Evaluation of serum adenosine deaminase and 5'-nucleotidase activities as probable markers in ovarian cancer.

Author information

  • 1Department of Biochemistry, Kasturba Medical College, 576 104 Manipal.

Abstract

Adenosine deaminase (ADA) and 5'-nucleotidase (5'-NT) activities were measured in sera of patients with ovarian cancer and patients with benign ovarian tumour. The results were compared with that of a control group consisting of healthy women. ADA levels were significantly increased (P<0.001) in the ovarian cancer group (n=50) but not in the benign group (n=28) when compared to the controls (n=20). The results indicate that ADA and 5'-NT levels may help to differentiate malignant conditions from benign tumours of the ovary in addition to the existing tests such as serum CA-125 levels and histopathological study.

KEYWORDS:

5′-NT; ADA; CA-125; Ovarian cancer

PMID:
23105561
[PubMed]
PMCID:
PMC3453859
Free PMC Article
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