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Indian J Clin Biochem. 2004 Jan;19(1):45-9. doi: 10.1007/BF02872388.

Evaluation of FSH, LH and testosterone levels in different subgroups of infertile males.

Author information

  • 1Institute of Genetics & Hospital for Genetic Diseases, Osmania University, Begumpet, 500 016 Hyderabad.

Abstract

Gonadotropins (FSH, LH) and testosterone are the prime regulators of germ cell development. Abnormal spermatogenesis is often associated with altered serum gonadotropins and testosterone. FSH, LH and testosterone levels were estimated in 96 infertile men of whom 35 were azoospermic, 35 were oligozoospermic, 11 were with varicocele and 15 were with histopathological abnormalities like hypospermatogenesis, spermatid arrest and sertoli-cell only syndrome. Results showed statistically significant (p<0.05), increase in the mean FSH and LH levels in all the infertile males studied when compared with the fertile controls (n=35). However, there is no significant difference in the mean levels of testosterone between the infertile and fertile men.

KEYWORDS:

FSH; Hypospermatogenesis; LH; Male infertility; Sertoli-cell only syndrome; Testosterone; Varicocele; spermatid arrest

PMID:
23105425
[PubMed]
PMCID:
PMC3453920
Free PMC Article
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