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J Trop Pediatr. 2013 Apr;59(2):95-9. doi: 10.1093/tropej/fms057. Epub 2012 Oct 26.

Establishment of the first newborn screening program in the People's Democratic Republic of Laos.

Author information

  • 1Neonatology and Paediatric Intensive Care Medicine, Department of General Paediatrics, Düsseldorf, Germany. thomas.hoehn@uni-duesseldorf.de

Abstract

OBJECTIVES:

The People's Democratic Republic of Laos belongs to the minority of countries worldwide without an established newborn bloodspot screening (NBS) system.

METHODS:

In 2008, we initiated a pilot project of a neonatal screening system in the delivery suites of the Laotian capital, Vientiane. Samples were analysed for thyrotropin-stimulating hormone and 17-hydroxyprogesterone.

RESULTS:

Altogether 11 362 samples were taken; an initially high recall rate dropped eventually to just above 4%. Two cases of hypothyroidism and one case of congenital adrenal hyperplasia were identified and received timely treatment.

CONCLUSIONS:

In summary, we have demonstrated the feasibility of establishing an NBS system in a low-resource setting as prevalent in Laos. Obstacles for the establishment of a general NBS covering the whole country include the question of financial cover, treatment costs, and adequate teaching and supervision of technicians and doctors.

PMID:
23104563
[PubMed - indexed for MEDLINE]
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