New twist on orphan receptor GPR88 function

Nat Neurosci. 2012 Nov;15(11):1469-70. doi: 10.1038/nn.3244.

Abstract

Ligands for G protein–coupled receptor 88 (GPR88) have not yet been found. A new study finds that GPR88 is important in the physiology of dorsal striatal projection neurons, as well as in behaviors involving this brain region.

Publication types

  • News
  • Comment

MeSH terms

  • Animals
  • Cues*
  • Female
  • Male
  • Motor Activity / genetics*
  • Neurons / physiology*
  • Receptors, G-Protein-Coupled / deficiency*

Substances

  • Gpr88 protein, mouse
  • Receptors, G-Protein-Coupled