Send to:

Choose Destination
See comment in PubMed Commons below
Fitoterapia. 2013 Jan;84:54-7. doi: 10.1016/j.fitote.2012.10.013. Epub 2012 Oct 24.

Sinoscrewtine, an alkaloid with novel skeleton from the roots of Sinomenium acutum.

Author information

  • 1Key Laboratory of Phytochemistry of Shaanxi Province, Baoji University of Arts and Sciences, Baoji 721013, China.


An alkaloid with novel skeleton, sinoscrewtine (1), has been isolated from the roots of Sinomenium acutum. Its structure was established by spectral analysis and X-ray crystallographic study, and its possible biosynthetic pathway was delivered. In vitro experiments, 1 showed weak injurious effects against H(2)O(2)/Aβ(25-35) induced oxidative injury in PC-12 cells and DPPH radical scavenging activity with IC(50) of 32.6μM.

Copyright © 2012 Elsevier B.V. All rights reserved.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk