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J Clin Anesth. 2012 Nov;24(7):555-60. doi: 10.1016/j.jclinane.2012.04.006.

Prevention of central venous catheter-related bloodstream infections: is it time to add simulation training to the prevention bundle?

Author information

  • 1Department of Anesthesiology, Cooper University Hospital, Camden, NJ 08103, USA. burden-amanda@cooperhealth.edu



To study the impact of adding simulation-based education to the pre-intervention mandatory hospital efforts aimed at decreasing central venous catheter-related blood stream infections (CRBSI) in intensive care units (ICU).


Pre- and post-intervention retrospective observational investigation.


24-bed ICU and a 562-bed university-affiliated, urban teaching hospital.


ICU patients July 2004-June 2008 were studied for the development of central venous catheter related blood stream infections (CRBSI).


ICU patients from July 2004-June 2008 were studied for the development of central venous catheter-related blood stream infections (CRBSI). PRE-INTERVENTION: mandatory staff and physician education began in 2004 to reduce CRBSI. The CRBSI-prevention program included online and didactic courses, and a pre- and post-test. Elements in the pre-intervention efforts included hand hygiene, full barrier precautions, use of Chlorhexidine skin preparation, and mask, gown, gloves, and hat protection for operators. A catheter-insertion cart containing all supplies and checklist were was a mandatory element of this program; a nurse was empowered to stop the procedure for non-performance of checklist items.


As of July 1, 2006, a mandatory simulation-based program for all intern, resident, and fellow physicians was added to teach central venous catheter (CVC) insertion.


Data collected pre- and post-intervention were CRBSI incidence, number of ICU catheter days, mortality, laboratory pathogen results, and costs.


The pre-intervention CRBSI incidence of 6.47/1,000 catheter days was reduced significantly to 2.44/1,000 catheter days post-intervention (58%; P < 0.05), resulting in a $539,902 savings (USD; 47%), and was attributed to shorter ICU and hospital lengths of stay.


Following simulation-based CVC program implementation, CRBSI incidence and costs were significantly reduced for two years post-intervention.

Copyright © 2012 Elsevier Inc. All rights reserved.

[PubMed - indexed for MEDLINE]
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