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Org Lett. 2012 Nov 2;14(21):5392-5. doi: 10.1021/ol302271w. Epub 2012 Oct 24.

Synthesis of indenes via Brønsted acid catalyzed cyclization of diaryl- and alkyl aryl-1,3-dienes.

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  • 1Department of Chemistry, Kangwon National University, Chuncheon 200-701, Republic of Korea.

Abstract

Substituted indenes can be synthesized via the Brønsted acid catalyzed cyclization of diaryl- and alkyl aryl-1,3-dienes. In this approach, treatment of symmetric or unsymmetric diaryl- and alkyl aryl-1,3-dienes with a catalytic amount of trifluoromethanesulfonic acid gives a variety of indene derivatives in good to excellent yields under mild conditions.

PMID:
23094690
[PubMed - indexed for MEDLINE]
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