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Genome Biol. 2012 Oct 23;13(10):173. doi: 10.1186/gb-2012-13-10-2012.

Balance of DNA methylation and demethylation in cancer development.

Abstract

Genome-wide 5-hydroxymethylome analysis of a rodent hepatocarcinogen model reveals that 5-hydroxymethylcytosine-dependent active DNA demethylation may be functionally important in the early stages of carcinogenesis.

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PMID:
23092522
[PubMed - in process]
PMCID:
PMC3491400
Free PMC Article

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