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BMJ Case Rep. 2012 Oct 12;2012. pii: bcr2012007128. doi: 10.1136/bcr-2012-007128.

Treatment of Stargardt disease with dobesilate.

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  • 1Departamento de Investigación, IRYCIS, Hospital Universitario Ramón y Cajal, Madrid, Spain.


Stargardt disease is a common inherited macular degeneration characterised by a significant loss in the central vision during the first or second decade of the life. Bilateral atrophic changes in the central retina are associated with degeneration of photoreceptors and underlying retinal pigment epithelium, and yellow flecks are extending from the macula. We present a patient with Stargardt disease treated with an intravitreal injection of dobesilate, showing an improvement of visual acuity 4 weeks after treatment.

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