Format

Send to:

Choose Destination
See comment in PubMed Commons below
Nat Commun. 2012;3:1143. doi: 10.1038/ncomms2140.

The genetic prehistory of southern Africa.

Author information

  • 1Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA. joseph_pickrell@hms.harvard.edu

Abstract

Southern and eastern African populations that speak non-Bantu languages with click consonants are known to harbour some of the most ancient genetic lineages in humans, but their relationships are poorly understood. Here, we report data from 23 populations analysed at over half a million single-nucleotide polymorphisms, using a genome-wide array designed for studying human history. The southern African Khoisan fall into two genetic groups, loosely corresponding to the northwestern and southeastern Kalahari, which we show separated within the last 30,000 years. We find that all individuals derive at least a few percent of their genomes from admixture with non-Khoisan populations that began ∼1,200 years ago. In addition, the East African Hadza and Sandawe derive a fraction of their ancestry from admixture with a population related to the Khoisan, supporting the hypothesis of an ancient link between southern and eastern Africa.

PMID:
23072811
[PubMed - indexed for MEDLINE]
PMCID:
PMC3493647
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Nature Publishing Group Icon for PubMed Central
    Loading ...
    Write to the Help Desk