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Curr Opin Pharmacol. 2012 Dec;12(6):667-72. doi: 10.1016/j.coph.2012.09.010. Epub 2012 Oct 4.

Communication between gastrointestinal bacteria and the nervous system.

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  • 1Instituto de Química, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile. javier.bravo@ucv.cl

Abstract

In the past few years, intestinal microbiota has emerged as a novel target for the treatment of gut-brain axis alterations. These include functional gastrointestinal disorders, such as irritable bowel syndrome (IBS), which can be comorbid with stress-related psychiatric conditions. Thus, modulation of the microbiota (e.g. with the use of probiotics) could be proposed as a novel strategy not only for the treatment of IBS but also as an adjuvant for psychiatric treatment of anxiety and depression.

Copyright © 2012 Elsevier Ltd. All rights reserved.

PMID:
23041079
[PubMed - indexed for MEDLINE]
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