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Cell Stem Cell. 2012 Oct 5;11(4):443-4. doi: 10.1016/j.stem.2012.09.010.

The satellite cell builds its nest under Notch's guidance.

Abstract

Recently in Developmental Cell, Bröhl et al. (2012) reported that Notch regulates muscle stem cell homing to its niche. Notch is required when myogenic cells cease producing new fibers and become sequestered between a newly forming basement membrane and the muscle fiber surface: the position that defines them as satellite cells.

Copyright © 2012 Elsevier Inc. All rights reserved.

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PMID:
23040471
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