Display Settings:

Format

Send to:

Choose Destination
Curr Opin Urol. 2012 Nov;22(6):517-20. doi: 10.1097/MOU.0b013e328358e191.

Varicocele repair in the era of modern assisted reproductive techniques.

Author information

  • 1Baylor College of Medicine, Houston, Texas 77030, USA.

Abstract

PURPOSE OF REVIEW:

This review looks at the literature on varicocele repair and its effect on assisted reproductive techniques. The effects of varicocele correction on improved sperm production have been well documented with semen analysis data. What remain to be elucidated are the causes of the varicocele effect and how correction of the resultant pathophysiology may affect the outcomes of modern assisted reproductive technology.

RECENT FINDINGS:

Basic science research shows us that varicoceles exert deleterious effects on Leydig cells, Sertoli cells, and germ cells via very different mechanisms. The effects of varicocele correction on the reproductive potential of sperm are less well understood. Clinical research has shown improved semen parameters, DNA integrity, and assisted reproductive technology outcomes after varicocele repair.

SUMMARY:

Varicocele correction presents a possible method to optimize a couples' reproductive potential or decrease the need for complex assisted reproductive technology.

PMID:
23026896
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Lippincott Williams & Wilkins
    Loading ...
    Write to the Help Desk