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Transplant Proc. 2012 Oct;44(8):2397-8. doi: 10.1016/j.transproceed.2012.07.002.

Aortic clamping in pancreas transplantation: is there any harm to the transplanted kidney graft?

Author information

  • 1Grupo Hepato and Bandeirantes and Beneficência Portuguesa Hospitals, São Paulo, Brazil. marcelo-perosa@uol.com.br

Abstract

INTRODUCTION:

Some special situations may require aortic clamping during pancreas transplantation (PT). The most important problem is ischemic injury to a previous transplanted kidney. We sought to demonstrate experience with aortic clamping in PT without special kidney allograft protection measures and its impact on kidney function.

METHODS:

Retrospective study that analyzed 6 patients who underwent PT (5 pancreas after kidney and 1 simultaneous pancreas-kidney) with aortic clamping. In all cases, the pancreas graft was placed on the right with retrocolic portal-enteric drainage. Serum creatinine was evaluated pre- and posttransplantation.

RESULTS:

The average clamping time was 19 minutes. The mean serum creatinine was 1.1, 1.15, 0.95, and 1.0, respectively, at pre and postoperative days 1 and 7 and at hospital discharge. Patient, kidney, and pancreatic graft survivals were 100%, 100%, and 83%, respectively.

CONCLUSION:

The need for aortic clamping in selected cases of PT did not seem to affect the transplanted kidney, even without protective measures, provided that the ischemic time was short.

Copyright © 2012 Elsevier Inc. All rights reserved.

PMID:
23026604
[PubMed - indexed for MEDLINE]
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