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Effect of artificial food colours on childhood behaviour.
Heart and Lung Institute, Brompton Hospital, London.
We performed an objective evaluation of 39 children whose behaviour was observed by their parents to improve on an artificial food additive free diet and to deteriorate with dietary lapses. Only 19 children completed a double blind placebo controlled challenge study with artificial food colours. In these children food colours were shown to have an adverse effect on a daily Conners' rating of behaviour, but most parents could not detect these changes. A pharmacological mechanism of food additive intolerance is proposed to explain these effects.
PMID: 2301986 [PubMed - indexed for MEDLINE]
PMCID: PMC1792406
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Cited by 3 PubMed Central articles
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The effects of a double blind, placebo controlled, artificial food colourings and benzoate preservative challenge on hyperactivity in a general population sample of preschool children.
Bateman B, Warner JO, Hutchinson E, Dean T, Rowlandson P, Gant C, Grundy J, Fitzgerald C, Stevenson J.
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[Arch Dis Child. 2004]
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ReviewHow a non-allergist survives an allergy clinic.
Rosenthal M.
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[Arch Dis Child. 2004]
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Effects of a few food diet in attention deficit disorder.
Carter CM, Urbanowicz M, Hemsley R, Mantilla L, Strobel S, Graham PJ, Taylor E.
Arch Dis Child. 1993 Nov; 69(5):564-8.
[Arch Dis Child. 1993]