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Appl Environ Microbiol. 2012 Dec;78(23):8474-6. doi: 10.1128/AEM.02183-12. Epub 2012 Sep 21.

Preferential utilization of D-lactate by Shewanella oneidensis.

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  • 1BioTechnology Institute and Department of Microbiology, University of Minnesota-Twin Cities, St. Paul, Minnesota, USA.

Abstract

Shewanella oneidensis couples oxidation of lactate to respiration of many substrates. Here we report that llpR (L-lactate-positive regulator, SO_3460) encodes a positive regulator of L-lactate utilization distinct from previously studied regulators. We also demonstrate D-lactate inhibition of L-lactate utilization in S. oneidensis, resulting in preferential utilization of the D isomer.

PMID:
23001660
[PubMed - indexed for MEDLINE]
PMCID:
PMC3497373
Free PMC Article
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