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Blood. 2012 Sep 20;120(12):2357-8.

AML cytogenetics: the complex just got simpler.

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  • 1Case Western Reserve University; Mayo Clinic.

Abstract

In this issue of Blood, Middeke et al, for the well-regarded Cooperative German Study Group, report a retrospective analysis in which they demonstrate that a hierarchial classification system for specific cytogenetic abnormalities in acute myeloid leukemia (AML) reveals that patients with abnormal 17p [abnl(17p)] and -5/5q- abnormalities have worse outcomes after allogeneic hematopoietic cell transplantation (HCT).

PMID:
22996657
[PubMed - indexed for MEDLINE]
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