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Chem Commun (Camb). 2012 Nov 4;48(85):10547-9.

Cascade imaging of proteolytic pathways in cancer cells using fluorescent protein-conjugated gold nanoquenchers.

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  • 1BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, Major of Nanobiotechnology, University of Science and Technology, Gwahangno, Yuseong, Daejeon 305-806, Republic of Korea.


The real-time monitoring of the caspase cascade in cancer cells during apoptosis was performed using various caspase substrate-linked fluorescent proteins-conjugated gold nanoparticles as a new imaging probe.

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