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Otolaryngol Clin North Am. 2012 Oct;45(5):1127-42. doi: 10.1016/j.otc.2012.06.013.

Evidence-based practice: endoscopic skull base resection for malignancy.

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  • 1Department of Otolaryngology-Head and Neck Surgery, University of North Carolina at Chapel Hill, 170 Manning Drive, CB 7070, Chapel Hill, NC 27599-7070, USA.


Successful outcomes of endoscopic approaches to benign sinonasal tumors have launched interest in expanding its use for sinonasal malignancy. Because of the heterogeneity and rarity of sinonasal malignancy, evidence for clinical outcomes of endoscopic approaches versus traditional craniofacial resection is low. Using the Oxford Center for Evidence-based Medicine guidelines, we present the existing evidence comparing both techniques for a variety of sinonasal malignancies.

Copyright © 2012 Elsevier Inc. All rights reserved.

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