Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Int J Hepatol. 2012;2012:158547. doi: 10.1155/2012/158547. Epub 2012 Aug 29.

Cell signals influencing hepatic fibrosis.

Author information

  • 1Department of Medicine, School of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.

Abstract

Liver fibrosis is the result of the entire organism responding to a chronic injury. Every cell type in the liver contributes to the fibrosis. This paper first discusses key intracellular signaling pathways that are induced during liver fibrosis. The paper then examines the effects of these signaling pathways on the major cell types in the liver. This will provide insights into the molecular pathophysiology of liver fibrosis and should identify therapeutic targets.

PMID:
22973518
[PubMed]
PMCID:
PMC3437636
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Hindawi Publishing Corporation Icon for PubMed Central
    Loading ...
    Write to the Help Desk