J Clin Psychiatry. 1990 Jan;51(1):32-3.

Treatment of clomipramine-induced anorgasmia with yohimbine: a case report.

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Department of Psychiatry, University of Michigan, Ann Arbor 48109-0118.

Abstract

Clomipramine (a tricyclic antidepressant with significant serotonin activity) causes a high incidence of anorgasmia. The authors describe the successful treatment of clomipramine-induced anorgasmia with yohimbine (an enhancer of norepinephrine activity) in a patient with obsessive compulsive disorder and major depression. The significance of this finding for the clinical management of antidepressant-induced sexual dysfunction and the impact of serotonergic-noradrenergic interaction on male sexual functioning are discussed.

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Cited by 1 PubMed Central article

The effect of amantadine on clomipramine induced sexual dysfunction in male rats. [Oman Med J. 2011]
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Treatment of clomipramine-induced anorgasmia with yohimbine: a case report.
Treatment of clomipramine-induced anorgasmia with yohimbine: a case report.
J Clin Psychiatry. 1990 Jan ;51(1):32-3.

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