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Nat Rev Drug Discov. 2012 Sep;11(9):655-6. doi: 10.1038/nrd3822.

Down's syndrome and Alzheimer's disease: towards secondary prevention.

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  • 1Janssen Research & Development, 1125 Trenton-Harbourton Road, Raritan, New Jersey 08560, USA. sness@its.jnj.com

Abstract

A public-private partnership to establish biomarkers of dementia in Down's syndrome could aid the development of preventive therapies for the dementia associated with both Down's syndrome and Alzheimer's disease, based on the apparent common pathogenic role of amyloid precursor protein in the two conditions.

PMID:
22935789
[PubMed - indexed for MEDLINE]
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