[Efficacy of ginseng drugs in experimental insulin-dependent diabetes and toxic hepatitis]

Patol Fiziol Eksp Ter. 1990 Sep-Oct:(5):49-52.
[Article in Russian]

Abstract

Drugs obtained from the roots and leaves of plantation ginseng and ginseng root tissue culture displayed a high antidiabetic and hepatoprotective activity in experiments on mice and rats. In alloxan diabetes these adaptogenic phyto-agents prevented alloxan-induced activation of processes of lipid peroxidation in the pancreas and demonstrated definite insulinogenic properties: they increased the basal content of insulin in blood and the glucose-dependent secretion of this hormone. In CCl4 acute toxic hepatitis the studies ginseng drugs reduced the disorders of hepatic detoxification and glycogen-synthesizing functions.

MeSH terms

  • Animals
  • Chemical and Drug Induced Liver Injury / drug therapy*
  • Diabetes Mellitus, Experimental / drug therapy*
  • Diabetes Mellitus, Type 1 / drug therapy*
  • Male
  • Mice
  • Mice, Inbred Strains
  • Panax*
  • Plants, Medicinal*